Meglitinides

Medicines in this class:
Nateglinide(nuh-TAY-gli-nide) - brand name Starlix
Repaglinide(re-PAG-lin-ide) – brand name Prandin

What does it do?

This medicine helps your body to:

  • Control blood glucose (sugar).

  • Release more insulin.

How do I take it?

  • This medicine comes in tablet form. Your doctor will tell you how much to take and how often to take it.

  • Take it 30 minutes before a meal. It begins to work as you are eating.

    • If you miss a dose before a meal: Skip that dose; and take your next dose before your next meal. Never take two doses at the same time.

    • If you skip a meal, you should skip your dose.

What are the possible side effects?

Low blood glucose (blood sugar) is the main side effect. It may occur when you miss a meal, exercise too long or drink alcohol.

Other side effects may include:

  • Diarrhea (loose, watery stools)

  • Feeling sick to your stomach

  • Feeling dizzy

  • Flu-like symptoms (fever, chills)

  • Cold symptoms (runny or stuffy nose, cough, sneezing or sore throat)

  • Weight gain.

When should I call the doctor?

Call your doctor right away if you have any of these problems:

  • Rapid weight gain.

  • Fever, chills or sore throat for more than 3 days.

  • A bad rash.

  • Any sign of an allergic reaction, such as:

    • Itchy skin.

    • Swelling in the face, hands, mouth or throat.

    • Tingling in the mouth or throat.

    • A tight feeling in the chest.

    • Trouble breathing.

What else should I know before taking this medicine?

  • Before taking this medicine, tell your doctor:

    • About all medicines you are taking, including over-the-counter drugs and herbal products.

    • If you have heart, liver or kidney disease.

    • If you have problems with your adrenal or pituitary glands.

    • If you are pregnant or breastfeeding.

    • If you have type 1 diabetes or have ketones in your urine (ketoacidosis).

  • Do not take this medicine if you have had an allergic reaction to any medicine in this class.

  • Always eat carbohydrate when drinking alcohol. Alcohol is more likely to lower your blood glucose while you are on this medicine.

  • This medicine may not work as well when you have a fever, injury, surgery or severe emotional stress.

For informational purposes only. Not to replace the advice of your health care provider.
Copyright © 2006 Fairview Health Services. All rights reserved. SMARTworks 520675 – Rev 11/15.

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For informational purposes only. Not to replace the advice of your health care provider. Copyright © 2006 Fairview Health Services. All rights reserved. SMARTworks 520675 – Rev 11/15.